Open AccessEnteric fever with severe pancytopenia in a four year girl
Author(s) -
R Pathak,
Aseem Sharma,
Ashish Khanal
Publication year - 2010
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.68
Subject(s) - medicine , pancytopenia , girl , enteric fever , pediatrics , typhoid fever , virology , bone marrow , psychology , developmental psychology
Typhoid fever and paratyphoid fever (also known as enteric fever) are severe systemic illnesses caused by salmonella typhi and S. paratyphi respectively. Enteric fever is prevalent in developing countries including Nepal, where it still remains as a major health problem. There have been reports of pancytopenia with enteric fever which has been attributed to mechanisms like bone marrow suppression, infection associated hemophagocytic syndrome and disseminated intravascular coagulation. We report here a case of severe pancytopenia in enteric fever as a result of bone marrow suppression due to systemic infection.
Keywords: enteric fever, pancytopenia, bone marrow suppression