Open AccessMetronidazole Induced Cerebellar Toxicity: A Case Report
Author(s) -
Shova Sapkota,
Aliska Niroula,
Rina Prajapati,
Subhani Sharma,
Krishna Dhungana
Publication year - 2021
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.6644
Subject(s) - medicine , metronidazole , neurotoxicity , toxicity , toxic encephalopathy , peripheral neuropathy , encephalopathy , cerebellum , magnetic resonance imaging , gastroenterology , antibiotics , pathology , radiology , endocrinology , microbiology and biotechnology , biology , diabetes mellitus
Metronidazole is a widely used antibiotic against bacterial and protozoan infections. Even though the therapeutic use of the drug is high, it is associated with some severe side effects like neurotoxicity such as optic neuropathy, peripheral neuropathy, encephalopathy and cerebellar toxicity. We present a case of a 55-years male presented with dysarthria, who had positive cerebellar sign and magnetic resonance imaging findings suggestive of metronidazole induced cerebellar toxicity following metronidazole therapy for two months in a case of liver abscess. And, the symptoms resolved after cessation of metronidazole.