
Ketamine gargling and postoperative sore throat
Author(s) -
Santosh Kumar Shrestha,
B Bhattarai,
Jashandeep Singh
Publication year - 2010
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.55
Subject(s) - medicine , sore throat , ketamine , throat , anesthesia , surgery
Tracheal intubation is a foremost cause of trauma to the airway mucosa, resulting in postoperative sorethroat (POST). The aim of the study was to compare the effectiveness of ketamine gargle with placebo in preventing POST after endotracheal intubation.
METHODS:
Forty patients scheduled for elective surgery under general anaesthesia were enrolled in this randomized, control trial. Patients were randomly allocated into two groups of 20 patients each: Group C, gargling with drinking water 30 ml; Group K, gargling with ketamine 50 mg in drinking water 30 ml for 30 s, 5 min before induction of anaesthesia. POST was graded at 4, 8, and 24 hours respectively after operation on a four- point scale (0-3).
RESULTS:
POST occurred more frequently in Group C, when compared with Group K at 4, 8, and 24 hours.
CONCLUSIONS:
Ketamine gargle reduces the incidence of POST after endotracheal intubation.