Open AccessPrevalence of p-16 Positive Laryngeal and Pharyngeal Tumors in Nepalese Population: A Hospital based Cross-sectional Study
Author(s) -
Bigyan Raj Gyawali,
Kunjan Acharya,
Ravindra Mohan Sapkota,
Dharma Baskota,
Bimal K. Sinha
Publication year - 2020
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.5132
Subject(s) - medicine , larynx , immunohistochemistry , pharynx , tonsil , pathology , stain , chronic tonsillitis , head and neck squamous cell carcinoma , carcinoma , tonsillectomy , head and neck cancer , staining , cancer , surgery
P16 overexpression is considered as a good prognostic marker for oropharyngeal squamous cell carcinoma. However, there are very few literatures on the prevalence and outcomes of p16 overexpression in non-oropharyngeal squamous cell carcinoma and benign head and neck tumors. The aim of our study was to estimate the hospital based prevalence of p16 positive laryngeal and pharyngeal tumors and to compare it with the prevalence of p16 expression in the non tumor tissue (tonsils).