Open AccessManagement of Locally Advanced Esophageal Cancer
Author(s) -
Basant Kumar Thakur,
Mukti Devkota,
Manish Chaudhary
Publication year - 2021
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.4299
Subject(s) - medicine , esophageal cancer , perioperative , stage (stratigraphy) , neoadjuvant therapy , cancer , chemotherapy , adenocarcinoma , esophageal adenocarcinoma , general surgery , oncology , surgery , paleontology , breast cancer , biology
Esophageal cancer is diagnosed usually at a locally advanced stage. Surgery alone has less optimal results and a multimodality approach has been established as the standard of care for cII-III stages of esophageal cancer. This review focuses on the recent evidences of management of esophageal cancer with various variations in approaches in Eastern and Western countries. The major difference is the selection of induction treatment. Till the results of some ongoing trials become available, most of the evidences support neoadjuvant chemoradiation followed by surgery for squamous cell carcinoma and perioperative chemotherapy and surgery for adenocarcinoma.