Open AccessMarkel Cell Carcinoma
Author(s) -
Sebastian Wallis,
A. Durham-Hall,
N Tondon,
TM Brotherstone,
Badri Man Shrestha
Publication year - 2010
Publication title -
journal of nepal medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 19
eISSN - 1815-672X
pISSN - 0028-2715
DOI - 10.31729/jnma.117
Subject(s) - medicine , merkel cell carcinoma , epidermis (zoology) , merkel cell , carcinoma , basal cell carcinoma , pathology , cell , basal cell , dermatology , oncology , anatomy , biology , genetics
Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis and are thought to function as touch receptors. Here, we describe a case of MCC in a 71-year-old female and provide an up-to-date review of the literature pertinent to the management of MCC.
KEYWORDS: merkell cell carcinoma, diagnosis, imunohistochemistry, management.