Open AccessKontrola antibiotika u mesu i mesnim proizvodima u Europskoj Uniji
Author(s) -
Nina Bilandžić,
Ivana Varenina,
Ines Varga,
Božica Solomun Kolanović,
Đurđica Božić Luburić
Publication year - 2019
Publication title -
meso
Language(s) - English
Resource type - Journals
eISSN - 1848-8323
pISSN - 1332-0025
DOI - 10.31727/m.21.3.4
Subject(s) - veterinary drug , european union , veterinary drugs , food safety , antibiotics , medicine , microbiology and biotechnology , veterinary medicine , food science , business , biology , chemistry , economic policy , chromatography
Today, more than 400 drugs in veterinary medicine are used in three main purposes, in the treatment of microbial infections, infection prevention, and growth promoters in order to achieve a faster animal growth. Residues of medicines in meat and meat products can have a number of negative effects on consumer health, ranging from hypersensitivity to cancerous, mutagenic or teratogenic effects, normal intestinal flora disorders, and antibiotic-resistant bacterial strains. In the European Union (EU), the largest meat producers are Spain, Italy, Germany, Poland, France and the United Kingdom, which also have the largest drug sales. The largest quantities of drugs sold were found for tetracyclines, penicillins and sulphonamides whose combined sales at EU level in 2015 were 69.6 % and in Croatia 76.7 %. EU members under Council Directive 96/23/EC carry out control of residues of veterinary drugs according to national residue monitoring plans (NRMP) in animals used for food production. Screening and confirmatory methods are used to control of drug residues. Most commonly, liquid chromatography in combination with tandem mass spectrometry is used. Today, priority is the development of effective multimethods that allow simultaneous analysis of residues of different antibiotic families. Every year, the European Food Safety Authority (EFSA) summarizes the results of the NRMP of the EU Member States in a joint report. The total number of non-compliant antibiotic results in meat samples in 2015 and 2016 was 250 and 195, respectively. The highest number of non-compliant results was found for tetracyclines. A coordinated and comprehensive control of veterinary medicines is established in the EU necessary for a high level of consumer health protection. The system of regulations just as well as analytical methods are constantly being upgraded and developed.