Open AccessTHE EFFECTIVNESS OF ANTI-INLAMMATORY THERAPY EVALUATED BY SYNOVIAL MEMBRANE VESSELS' DOPPLER PARAMETERS IN PATIENTS SUFFERING ON RHEUMATOID ARTHRITIS
Author(s) -
В. М. Ждан,
V.G. Lebid,
I.V. Ivanytckyi,
Yu. Ischeykina,
Олександр Іванович Катеренчук
Publication year - 2020
Publication title -
aktualʹnì problemi sučasnoï medicini: vìsnik ukraïnsʹkoï medičnoï stomatologìčnoï akademì
Language(s) - English
Resource type - Journals
eISSN - 2077-1126
pISSN - 2077-1096
DOI - 10.31718/2077-1096.20.4.40
Subject(s) - rheumatoid arthritis , medicine , pannus , ultrasound , synovitis , doppler ultrasound , arthritis , radiology , cardiology , surgery
Rheumatoid arthritis is known as a highly prevalent disease worldwide, often resulting in stable loss of capacity for work or complete disability over short period from the onset. Detected changes in the joint morphology may depend on the basic treatment received as well as depend on the level of control over the disease progression. The aim of this work is to study the diagnostic potential of Doppler ultrasound technique and Dopplerography in assessing the severity of changes in the knee joints depending on the received basic treatment and the level of control over disease in patients with rheumatoid arthritis. Correlation analysis carried out to compare the severity of bone erosions' indicators and the level of C-reactive protein has revealed no significant correlations. At the same time, there has been found a strong correlation between the level of C-reactive protein values and the blood circulation rate in the arteries of the pannus in all studied groups at the beginning of treatment and in 6 months of the therapy (r≥0.65, p≤0.03). The obtained results clearly demonstrate the effectiveness of the ultrasound diagnostics, especially Doppler indicators, in assessing the effectiveness of the basic treatment for patients with rheumatoid arthritis.