Open AccessDIASTOLIC FUNCTION OF LEFT VENTRICLE IN PATIENTS WITH CORONARY ARTERY DISEASE DURING THE DEVELOPMENT OF ACUTE MYOCARDIAL INFARCTION
Author(s) -
Eric Sid,
О. В. Соловйов
Publication year - 2020
Publication title -
aktualʹnì problemi sučasnoï medicini: vìsnik ukraïnsʹkoï medičnoï stomatologìčnoï akademì
Language(s) - English
Resource type - Journals
eISSN - 2077-1126
pISSN - 2077-1096
DOI - 10.31718/2077-1096.20.2.85
Subject(s) - myocardial infarction , medicine , cardiology , ventricle , electrocardiography in myocardial infarction , angina , infarction , diastole , coronary artery disease , blood pressure
Acute myocardial infarction is still remaining as one of the most challenging in modern cardiology. Impaired diastolic function of the left ventricle is one of the manifestations of myocardial dysfunction in coronary heart disease and one of the early prognostic criteria. Therefore, the investigation of this group of patients is especially relevant to assess the risk of possible complications and their timely correction. The present study was aimed at evaluating diastolic function of the left ventricle in patients with ischemic heart disease in the development of acute myocardial infarction. Materials and methods. The results of the study are based on a comprehensive survey of 477 patients with coronary heart disease: 280 patients with ST-segment elevation myocardial infarction, 91 individuals with non-ST-segment elevation myocardial infarction and the control group included 76 patients with angina pectoris (II and III functional class, each subgroup of 38 people). All 477 were comparable with regard to age, sex, and social status. Results. The level of DT was significantly higher in the ST-segment elevation myocardial infarction group and when compared to non ST-segment elevation myocardial infarction, 186.50 [173.00-242.00] ms versus 224.00 [182.00-244.00] ms, respectively, (p <0.05). There were similar differences in IVRT values between the groups of patients. The highest relative risk among the patients with ST-segment elevation myocardial infarction was significantly found out in the pseudonormal type, and during the development of Q-Myocardial infarction it was RR = 1.52, 95% CI RR 1,02-2,25. The increase in the relative risk was for the stimulation of the mitral flow during the development of Q-Myocardial infarction and made up RR = 1,31, 95% CI RR 1,11-1,55. Conclusions. 1. The patients with acute myocardial infarction demonstrated impaired diastolic function of the left ventricle, with a predominance of pseudonormal type among the patients with ST-segment elevation myocardial infarction and impaired relaxation in patients with non-ST-segment elevation myocardial infarction. 2. The increase in relative risk among patients with ST-segment elevation myocardial infarction has been well established for the pseudonormal type.