Open AccessCHANGES IN ULTRASTRUCTURE OF CALF MUSCLE AND MYOCARDIUM UNDER PHYSICAL LODADING IN EXPERIMENT
Author(s) -
V. L. Voitenko,
Лариса Гунина
Publication year - 2020
Publication title -
aktualʹnì problemi sučasnoï medicini: vìsnik ukraïnsʹkoï medičnoï stomatologìčnoï akademì
Language(s) - English
Resource type - Journals
eISSN - 2077-1126
pISSN - 2077-1096
DOI - 10.31718/2077-1096.20.2.114
Subject(s) - exertion , microcirculation , skeletal muscle , ultrastructure , pathological , physiology , circulatory system , biology , medicine , anatomy , cardiology
Long-term physical activity causes restructuring in the various functions and systems of the body, which are, as a rule, adaptive in nature and occur at all levels of the structural organization of the body. The question of changes in the functional state of the cardiovascular system and, especially, the microcirculatory section of the circulatory system in normal and under the physical exertion and their relationship with ultrastructural remodelling in tissues, cells and cellular organelles is still remaining unclear. The aim of the study was to assess structural changes in the tissues of the calf muscle and myocardium that cause the development of adaptive mechanisms in response to prolonged physical exertion. We studied the structural components of tissue samples of calf muscle and the apex of the heart taken from mature Wistar male rats weighing 220-250 g in mass exposed to prolonged physical exertion by using electron microscopy. It has been shown that a long and intense physical loading causes the development of a number of compensatory-adaptive reactions directed at improving microcirculation processes, oxygen supply of skeletal muscles and myocardium, as well as maintaining an adequate level of metabolic processes. A detailed assessment of the functional state of the tissues studied is necessary for the early detection of signs of maladjustment under the constant loading in sports and the prevention of pathological states.