DYNAMICS OF WOUND HEALING AFTER INTRAORAL PIERCING WITH MEDICAL STEEL CLIPS IN EXPERIMENTAL ANIMALS

. In modern dentistry, medical steel, along with other materials used for dental implantation, is considered as biocompatible or bio-tolerant materials. Among the commonest complications caused by piercing, there are hypertrophic scarring, pain, swelling and infection. Therefore, the research on clinical and morphological changes in tongue and cheek tissues during experimental piercing with medical steel clips on animals and further evaluation of the consequences of this procedure seem to be quite relevant. The purpose of the study was to determine the effect of clips made of medical steel on the dynamics of the wound healing in tissues of the cheek and tongue following the implantation in test animals. Materials and methods. The experiment was conducted on the chinchilla line rabbits (n=8) in 2015. The animals were implanted with medical steel clips in soft tissue of the tongue and cheeks. Histological studies were performed on 7th, 14th, 28th and 60th days following the implantation to study the dynamics of the change in the pierced channel. Results and conclusions. The study has shown the purulent process in the tongue and cheeks tissues following the implantation of medical steel clips can be observed from the 7th to 60th days. Thus, we can suggest that the damaging effect of medical steel clips on tongue and cheek tissues in the test animal promotes purulent inflammation. The rabbits with implanted clips in the tongue and cheek had broad wound channels, containing purulent exudates, inflammatory infiltrates were found in the walls of the wound channel. During the experiment, the histological specimens of the cheeks and tongue showed a large amount of granulation tissue, signs of immaturity and secondary inflammation, slow transformation of granulation tissue into the connective tissue that causes a lack of complete epithelisation and promotes deep skin wounds. The impairment of nerve endings in the form of oedema of the endo- and perineuria as a consequence of the implantation of medical steel clips can be manifested by persistent pain syndrome, loss of local sensitivity and distortion of taste sensation. In future, we are planning to investigate the dynamics of the wound healing after intraoral implantation of clips made of other materials in the test animals.