Open AccessCOMPARATIVE-AGE CHARACTERISTICS OF THE STATE OF THE NEUROVEGATIVE REGULATION OF THE GASTROINTESTINAL TRACT IN INTENSIVE CARE PATIENTS
Author(s) -
D. Shkrupii,
А. І. Mogylnyk,
E. Sonnik
Publication year - 2019
Publication title -
aktualʹnì problemi sučasnoï medicini: vìsnik ukraïnsʹkoï medičnoï stomatologìčnoï akademì
Language(s) - English
Resource type - Journals
eISSN - 2077-1126
pISSN - 2077-1096
DOI - 10.31718/2077-1096.19.3.100
Subject(s) - autonomic nervous system , gastrointestinal tract , medicine , intensive care , sympathetic nervous system , physiology , intensive care medicine , heart rate , blood pressure
. The autonomic nervous system is considered to be the leading adapter of the body to changing conditions of existence The intestine is subjected to massive irritating effects, and therefore is actively regulated by the autonomic nervous system, and itself, at the same time, is its regulator. In intensive care conditions, autonomic reactions change under the influence of critical state inducers. The purpose of the study: a comparative analysis of the neurovegetative regulation of the gastrointestinal tract in patients under intensive care in an age-related aspect. Materials and methods. Under observation were 70 patients in need of intensive care. Of these, 30 are children of the first month of life and 40 are adult patients. The study applied methods of cardiointervalography and assessment of the degree of gastrointestinal failure syndrome. The results of the study. The analysis of cardiointervalograms showed a relatively equal tension of the sympathetic part of the autonomic nervous system, regardless of age. However, in children, in comparison with adults, a more pronounced relative dysbalance of autonomic regulation in favor of humoral sympathetic influences is noted, which significantly increases the stress index in childhood. Despite the pronounced activity of the humoral channel for regulating autonomic homeostasis, it was not a factor affecting the severity of gastrointestinal failure syndrome. Therefore, this factor may be trigger in the formation of intestinal dysfunction, but not determining in the formation of its severity. Correlation in the adult group indicates the predominance of parasympathetic influences in the formation of gastrointestinal failure syndrome. Among children, unlike adults, the formation of this syndrome is associated not only with changes in the parasympathetic department, but with hypersympaticotonia. Conclusions. Regardless of the age, in patients with intensive care, an increase in tension of the sympathetic part of the autonomic nervous system is noted. In children, compared with adults, a markedly pronounced activity of humoral sympathetic influences was noted. At the same time, parasympathetic activity is the decisive factor in the progression of gastrointestinal failure syndrome in adults, and hypersympathicotonia in children.