Open AccessFirst application of 7-T ultra–high field diffusion tensor imaging to detect altered microstructure of thalamic-somatosensory anatomy in trigeminal neuralgia
Author(s) -
John W Rutland,
Kuang-Han Huang,
Corey M. Gill,
Dillan F. Villavisanis,
Judy Alper,
Gaurav Verma,
Joshua B. Bederson,
Bradley N. Delman,
Raj Shrivastava,
Priti Balchandani
Publication year - 2020
Publication title -
journal of neurosurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.564
H-Index - 210
eISSN - 1933-0693
pISSN - 0022-3085
DOI - 10.3171/2019.6.jns19541
Subject(s) - medicine , somatosensory system , thalamus , fractional anisotropy , diffusion mri , trigeminal neuralgia , neurovascular bundle , somatosensory evoked potential , tractography , anatomy , neuroscience , magnetic resonance imaging , radiology , anesthesia , psychology , psychiatry
Trigeminal neuralgia (TN) is a debilitating neurological disease that commonly results from neurovascular compression of the trigeminal nerve (CN V). Although the CN V has been extensively studied at the site of neurovascular compression, many pathophysiological factors remain obscure. For example, thalamic-somatosensory function is thought to be altered in TN, but the abnormalities are inadequately characterized. Furthermore, there are few studies using 7-T MRI to examine patients with TN. The purpose of the present study was to use 7-T MRI to assess microstructural alteration in the thalamic-somatosensory tracts of patients with TN by using ultra-high field MRI.