Open AccessComparison of the Clinical Recovery after Nerve Defect Reconstruction Using 4 Different Methods – Experimental Model
Author(s) -
Marin Andrei,
Anica Dricu,
Georgiana Gabriela Marin,
Carmen Giuglea
Publication year - 2021
Publication title -
modern medicine
Language(s) - English
Resource type - Journals
eISSN - 2360-2473
pISSN - 1223-0472
DOI - 10.31689/rmm.2021.28.2.223
Subject(s) - aorta , in vivo , medicine , nerve cells , nerve guidance conduit , sciatic nerve , epineurial repair , biomedical engineering , anatomy , surgery , biology , microbiology and biotechnology
There are several possibilities for repairing a nerve defect. These include nerve grafting, tissues for bridging, biological or synthetic nerve conduits. Such conduits, alone or filled with different tissues or substances, may be the key for a major breakthrough in the modern treatment of nerve defects. The easiest way to research these new methods is by experimental in vivo research on live animals – such as the Wistar rats. The following article aims to compare 4 different types of repairs for nerve defects: the nerve graft, a biologic nerve conduit (rat aorta), rat aorta with platelet rich plasma and rat aorta with stem cells.