Open AccessNonconvulsive Status Epilepticus Caused by Cerebrospinal Fluid Dissemination of a Salivary Duct Carcinoma: A Case Report
Author(s) -
Takahisa Kato,
Junya Tsurukiri,
Hidefumi Sano,
Takeo Nagura,
Mariko Moriya,
Hiroki Suenaga,
Kyosuke Matsunaga,
Takeshi Kanemura,
Yuki Ueta,
Takao Arai
Publication year - 2022
Publication title -
jma journal
Language(s) - English
Resource type - Journals
eISSN - 2433-3298
pISSN - 2433-328X
DOI - 10.31662/jmaj.2021-0108
Subject(s) - status epilepticus , salivary duct carcinoma , medicine , parotid gland , cerebrospinal fluid , metastasis , pathology , etiology , brain metastasis , epilepsy , lymph , salivary gland , carcinoma , cancer , psychiatry
Salivary duct carcinoma (SDC) is a rare and highly aggressive salivary gland tumor with rapid growth, distant metastasis, and a high recurrence rate. Moreover, the parotid gland is the most common site with a poor prognosis. A lower frequency of distance metastasis to the liver, skin, and brain has also been reported, although the lungs, bones, and lymph nodes are the most common sites of SDC metastasis. We report a case of nonconvulsive status epilepticus (NCSE) in a 73-year-old male comatose patient having SDC of the parotid gland with an unusual metastasis to the skin and brain diagnosed by frequent cerebrospinal fluid examinations. Meningeal carcinomatosis usually has a poor prognosis, and NCSE is a reversible cause of altered mentation. Clinicians should know the unique set of epilepsy etiologies in patients with malignant tumors.