Open AccessA 9-Year Old Boy with Leukemia and Oral Manifestation: A Case Report and Review of Literature
Author(s) -
Alieh Safari,
Farzad Kompani,
Sara Memarian,
Maryam Monajemzadeh,
Rahman Khosravi,
Behdad Gharib
Publication year - 2016
Publication title -
galen medical journal
Language(s) - English
Resource type - Journals
eISSN - 2588-2767
pISSN - 2322-2379
DOI - 10.31661/gmj.v5i4.576
Subject(s) - medicine , leukemia , presentation (obstetrics) , myeloid leukemia , lymphoblastic leukemia , malignant histiocytosis , disease , physical examination , bone marrow , pediatrics , dermatology , pathology , surgery , histiocyte
Background: Childhood leukemia is not a common disease. However, the most common malignant neoplasms in children are the leukemias, and 77% of these cases are acute lymphoblastic leukemia (ALL). Case Report: We report a case of precursor B-cell ALL, initially presented by unusual manifestations such as; teeth ache, loose teeth and gum swelling, knee pain and a normal cell blood count (CBC). It was first considered to be Histiocytosis. Several laboratory workups have been performed to rule out the immunologic, infectious and rheumatologic diseases. A bone marrow aspiration revealed the diagnosis of leukemia. However, acute myeloid leukemia is more famous for being accompanied by oral presentation; our patient was afflicted by ALL. The patient was first referred to a dentist for the oral manifestations. Conclusion: This case reminds the importance of systemic evaluation of localized signs and symptoms in children and detailed history taking, follow-ups and physical examination.[GMJ.2016;5(4):215-18]