Open AccessCombined Factor V and Factor VIII Deficiency: A Case Report
Author(s) -
Ehsan Shahverdi,
Hassan Abolghasemi,
Fardin Dolatimehr,
Sara Beheshtian,
Shima Melatshahi Chaeichi,
Avishan Masoumi
Publication year - 2016
Publication title -
galen medical journal
Language(s) - English
Resource type - Journals
eISSN - 2588-2767
pISSN - 2322-2379
DOI - 10.31661/gmj.v5i1.580
Subject(s) - medicine , consanguineous marriage , girl , pediatrics , coagulation , coagulation disorder , factor v , consanguinity , genetics , biology , thrombosis
Background: Combined factor V and factor VIII deficiency (F5F8D, OMIM 227300) is a rare autosomal recessive bleeding disorder. It seems more common among Jews and Iranians, particularly in regions with frequent consanguineous marriages. Case Report: We describe a 5-yearold girl born out of consanguineous marriage with a complaint of prolonged bleeding after dental extraction. There were no history of spontaneous bleeding and other coagulation defect symptoms. Conclusion: In frequent consanguineous marriage regions, inherited deficiency of factor V and VIII should be considered in patients with coagulation defect symptoms.[GMJ. 2016;5(1):42-44]