Open AccessRole of Zinc in Improvement, Prevention, and Treatment of the Noncommunicable Oral Diseases: Review of Literature
Author(s) -
Farzaneh AghaHosseini,
MahdiehSadat Moosavi,
Sanam Talaei
Publication year - 2021
Publication title -
galen medical journal
Language(s) - English
Resource type - Journals
eISSN - 2588-2767
pISSN - 2322-2379
DOI - 10.31661/gmj.v10i0.2071
Subject(s) - medicine , oral lichen planus , stomatitis , dermatology , burning mouth syndrome , leukoplakia , disease , oral leukoplakia , oral cavity , recurrent aphthous stomatitis , basal cell , dentistry , cancer
Zinc, as the second most abundant trace element present in the living organisms after iron,
plays a key role in the structural, catalytic, and signaling felds. Beyond the numerous systemic symptoms of zinc defciency, it may also contribute to dierent processes of oral diseases.
The articles were collected from three search engines including PUBMED, GOOGLE SCHOLAR, and SCOPUS. The search keywords are as follows: Zinc, trace elements, zinc defciency,
oral diseases, oral lesions, recurrent aphthous stomatitis, oral lichen planus, oral squamous cell
carcinoma, burning mouth syndrome, xerostomia, neuropathy. Many diverse articles including
original article, case report/case series, and review articles were collected. Several studies have
investigated the role of zinc and its defciency in the development of various types of noncommunicable oral lesions including recurrent aphthous stomatitis (RAS), oral lichen planus (OLP),
precancerous lesions of the oral cavity (leukoplakia and submucosal fbrosis), oral cancer, xerostomia and burning mouth syndrome, periodontal disease, and Caries. Therefore, the present
research was conducted to review the previous studies performed in this feld.
[GMJ.2021;10:e2071]