Open AccessThe role of herpesviruses 6 and 7 in the development of chronic fatigue syndrome: a review of literature and description of clinical cases
Author(s) -
Vladyslav Tsaryk,
A. K. Novoskoltsev
Publication year - 2018
Publication title -
lìkarsʹka sprava/lìkarsʹka sprava
Language(s) - English
Resource type - Journals
eISSN - 2706-8803
pISSN - 1019-5297
DOI - 10.31640/vd.7-8.2018(4
Subject(s) - chronic fatigue syndrome , viremia , ganciclovir , medicine , immunology , fibromyalgia , cytomegalovirus , intensive care medicine , herpesviridae , human immunodeficiency virus (hiv) , psychiatry , virus , human cytomegalovirus , viral disease
At the issue represented the etiopathogenesis of the chronic fatigue syndrome of (CFS) with immune dysfunction. Many doctors consider this problem only from the point of view of non-psychological disorders requiring only psycho-correction and non-drug treatment. However, syndromocomplex of CFS includes not only neuropsychiatric disorders, but also fibromyalgia syndrome, unexplained genesis, lymphadenopathy, non-specific polyarthralgias. It is also controversial about the feasibility of treating type 6 herpesviruses and type 7 viruses. Some authors consider the need for antiviral therapy only when reactivating the herpesvirus infection, in the transplantation of organs and tissues. However, for frequent HHV-7 and HHV-6 viremia remains resistant to ganciclovir, unlike CMV and EBV, which is successfully controlled by viremia.