Open AccessPECULIARITIES OF CLINICAL PRESENTATION AND SURGICAL TREATMENT OF PATIENTS WITH OCCULT CARCINOMA OF GALLBLADDER
Author(s) -
V. І. Коlomiytsev,
О. M. Syroid,
О. В. Лукавецький
Publication year - 2018
Publication title -
lìkarsʹka sprava/lìkarsʹka sprava
Language(s) - English
Resource type - Journals
eISSN - 2706-8803
pISSN - 1019-5297
DOI - 10.31640/vd.7-8.2018(15
Subject(s) - occult , medicine , gallbladder , gastroenterology , cholecystectomy , carcinoma , stage (stratigraphy) , gallbladder cancer , radiology , pathology , paleontology , alternative medicine , biology
141 patients with gallbladder cancer (GBC) were operated from 2003 to 2016. 29 (20.6 %) patients were diagnosed with occult GBC. In most (88.4–100 %) cases, GBC was accompanied by cholelithiasis; furthermore, cholelithiasis lasted much longer if patients had occult GBC (P = 0.032). The signs of acute or chronic calculous cholecystitis were clinically detected in patients with occult GBC. For this group of patients, tumours were more often located in the body or fundus of gallbladder (P 0.3) and the presence of distant metastases (P > 0.4) were not statistically different from those in patients with manifest GBC. Cholecystectomy was performed in all patients with occult GBC and in 50 (44.6 %) patients with manifest GBC (P < 0.001). Liver resection and/or operation on the extrahepatic bile ducts was performed in 8 (27.6 %) and 50 (44.6 %) patients, respectively (P < 0.001). Postoperative complications were detected in 2 (6.9 %) patients with occult GBC and in 27 (24.1 %) patients with manifest GBC (P < 0.05). ІІІ–ІV stage of tumour was identified in 5 (17.2 %) patients with occult GBC. Treatment result in this case was less satisfactory.