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Prognosis of the fetal distress in pregnant women with hypertensive disorders and hyperhomocyteinemia
Author(s) -
N. A. Gaistruk,
O. O. Mazchenko,
A. N. Gaistruk,
I.V. Prolygina,
S.A. Tarasiuk
Publication year - 2020
Publication title -
lìkarsʹka sprava/lìkarsʹka sprava
Language(s) - English
Resource type - Journals
eISSN - 2706-8803
pISSN - 1019-5297
DOI - 10.31640/jvd.5-6.2020(6
Subject(s) - fetal distress , medicine , pregnancy , fetus , distress , obstetrics , incidence (geometry) , clinical psychology , genetics , physics , optics , biology
In the article the reisapresentation of mathematical prediction of fetal distress in pregnant women with hypertensive disorders and hyperhomocyteinemia. In the basis of the model, the factors that significantly affect the chance of an unfavorable course of pregnancy for a given group of women. The clinical significance of the prediction is necessary for the formation of a differentiated approach to the management of pregnancy, depending on the probability of perinatal complications resulting from the application of the model. The most important role belongs to the detection of factors, which preceding development distress of fatus and are accompanied by the presence of extragenital diseases and patology of pregnancy. All of these factors should be known, when evaluated prenatal fetal condition, placental function, determination of laboratory-instrumental research methods for pregnancy with hypertensive disorders. Based on the results of the research, the algorithm of examination of the pregnant women with fetus distress symptoms was created. Parametric criteria are described for the diagnosis of fetal distress based on the determination of the level of homocysteine and oxidative modifection of protein in the blood of pregnant women. The original metod of forecasting the development of the fetal distress in pregnant women with hypertension is proposed. The use of drugs with metabolic action has led to credibly positive results, namely the reduction of the incidence of fetal distress, asphyxiation of newborns and prenatal morbidity and mortality. As a result of this we can see an improvement in reproductive health of women with hypertensive disorders.

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