Open AccessPrevalence of Extensively Drug-Resistant Tuberculosis: a Descriptive Study
Author(s) -
Пасечник Оксана Александровна,
А А Зимогляд,
И. В. Ярусова,
Витрив Станислав Васильевич,
Блох Алексей Игоревич
Publication year - 2018
Publication title -
èpidemiologiâ i vakcinoprofilaktika
Language(s) - English
Resource type - Journals
eISSN - 2619-0494
pISSN - 2073-3046
DOI - 10.31631/2073-3046-2018-17-4-13-19
Subject(s) - tuberculosis , medicine , epidemiology , drug resistance , extensively drug resistant tuberculosis , population , drug , drug resistant tuberculosis , mycobacterium tuberculosis , environmental health , pediatrics , pathology , pharmacology , microbiology and biotechnology , biology
Background. Extensively drug-resistant tuberculosis (XDR-TB) is a threat to community health. Goal. The estimation of the prevalence of extensively drug-resistant tuberculosis in Omsk region, along with the clinical and epidemiological description of patients with XDRTB. Methodology. A retrospective descriptive epidemiologic research of tuberculosis morbidity in Omsk region in 2006–2017 was conducted.Results. The prevalence of extensively drug-resistant tuberculosis in Omsk region in 2006–2017 was stable at 35.6 per 100ths population with Tinc.=1.0%. The prevalence of extensively drug-resistant tuberculosis in Omsk region was 13.6 per 100ths population (n = 267). Among patients with XDR-TB the majority was of young working age 25–44 years (63.2%), male gender (80.9%), officially unemployed (75.6%), ill for at least 3 years (57.0%), suffering from infiltrative pulmonary tuberculosis (69.2%) and HIV-infected (31.8%). The resistance to seven first and second line antituberculosis drugs was found in 10.1% of patients with XDR-TB. Conclusions. The optimisation of approaches to the organization of additional measures for the prevention of extensively drug-resistant tuberculosis is needed.