Open AccessImmunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia
Author(s) -
А. В. Корнева,
В. Б. Николаев,
Т. А. Иванова,
В. И. Дубровина,
Г. Б. Мухтургин,
Е Ю Марков,
Т. П. Старовойтова,
А. В. Мазепа,
Т. Т. Шкаруба,
С. В. Балахонов
Publication year - 2018
Publication title -
èpidemiologiâ i vakcinoprofilaktika
Language(s) - English
Resource type - Journals
eISSN - 2619-0494
pISSN - 2073-3046
DOI - 10.31631/2073-3046-2018-17-2-46-49
Subject(s) - francisella tularensis , tularemia , microbiology and biotechnology , subspecies , biology , francisella , virology , virulence , biochemistry , zoology , gene
Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the preparations from F. tularensis urea lysates are not toxic for experimental animals. Besides, CW of F. tularensis А-61 subsp. mediasiatica and F. tularensis B-399 A-Cole subsp. tularensis possess immunogenic activity in experimental tularemia caused by F. tularensis 306 subsp. holarctica.