Open AccessPathological Changes in Respiratory Part of Lungs White Mice with Experimental Plague
Author(s) -
С. А. Витязева,
Т. П. Старовойтова,
Г. Б. Мухтургин,
В. И. Дубровина,
С. В. Балахонов
Publication year - 2015
Publication title -
èpidemiologiâ i vakcinoprofilaktika
Language(s) - English
Resource type - Journals
eISSN - 2619-0494
pISSN - 2073-3046
DOI - 10.31631/2073-3046-2015-14-5-67-71
Subject(s) - yersinia pestis , plague (disease) , biology , plasmid , pathological , respiratory system , immune system , lung , microbiology and biotechnology , virology , pathology , immunology , virulence , gene , medicine , anatomy , genetics
The paper presents data on changes in the respiratory part of lungs of white mice with experimental plague caused by Yersinia рestis strains with different plasmid composition of Tuva and Gorno-Altaisk natural foci of plague and breeding clones. Morphological and structural changes in the lungs, which appear different degree of activation of the immune response and the severity of the pathological process caused by Y. pestis subsp. altaica and Y. pestis subsp. pestis and their isogenic plasmid options.