Open AccessInfluence of Bacillus anthracis 34F2 Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)
Author(s) -
V. V. Voytkova,
В. И. Дубровина,
S. A. Lukyanov,
O. V. Yuryeva,
О Б Колесникова,
К. М. Корытов,
Г. П. Александрова,
V. P. Iljin,
С. В. Балахонов
Publication year - 2015
Publication title -
èpidemiologiâ i vakcinoprofilaktika
Language(s) - English
Resource type - Journals
eISSN - 2619-0494
pISSN - 2073-3046
DOI - 10.31631/2073-3046-2015-14-2-107-112
Subject(s) - bacillus anthracis , adjuvant , antigen , microbiology and biotechnology , lymphocyte , immunology , biology , chemistry , bacteria , genetics
Study of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is demonstrated. However, content of the B-lymphocyte circulating subpopulations depends on the time of observation. Co-AG exhibits adjuvant properties enhanced the immunogenic features of the S-2 B. anthracis 34F2 Sterne that may indicate its availability as an adjuvant in the construction of chemical vaccines.