Open AccessDevelopment of Recombinant Leptospira Antigenes for the Purpose of Creation of Immunoassay Test Kit for Diagnosis of Leptospirosis
Author(s) -
V. N. Kulikov,
A. A. Kozarenco,
Н. К. Токаревич,
N Stoyanova
Publication year - 2015
Publication title -
èpidemiologiâ i vakcinoprofilaktika
Language(s) - English
Resource type - Journals
eISSN - 2619-0494
pISSN - 2073-3046
DOI - 10.31631/2073-3046-2015-14-2-10-12
Subject(s) - leptospira , immunoassay , recombinant dna , leptospirosis , antigen , virology , biology , computational biology , gene , antibody , immunology , genetics
Species-specific recombinant proteins of leptospira are genetically engineered by the method of gene manipulation. Their high activity and antigenic specificity are established. On the basis of these proteins an immunoassay test kit for detecting JgG to Leptospira is constructed.