Open AccessINFLUENCE OF INTENSIVE PHYSICAL LOADS ON OXIDATIVE STRESS AND ANTIOXIDANT CHANGES IN THE ATHLETES ORGANISM
Author(s) -
С.А. Алиев
Publication year - 2020
Publication title -
chronos journal
Language(s) - English
Resource type - Journals
ISSN - 2658-7556
DOI - 10.31618/2658-7556-2020-29-2-4
Subject(s) - superoxide dismutase , catalase , antioxidant , malondialdehyde , oxidative stress , glutathione , chemistry , biochemistry , medicine , enzyme
The article substantiates the formulation of experimental work on the study of adaptive features of antioxidant factors in the body's defensive reactions to physical activity. The influence of physical activity on the oxidative situation in muscles is discussed; the results of studies of LPO intensity, (dynamics of the level of malondialdehyde), the activity of enzymes involved in antioxidant protection (glutathione – S – transferases, catalases, and super oxidants) in blood plasma and erythrocytes of wrestlers during annual training macrocycle are described. It was determined that the level of malondialdialdehyde significantly exceeds the control throughout the year. MDA concentration reaches a maximum at the end of the competition period and is not restored during the rest period. The activity of superoxide dismutase and catalase is significantly reduced and does not return to control values during the year. The mentioned changes confirm chronic decompensation in the antioxidant defense system. A leading enzyme that protects against active forms of oxygen in the blood plasma and red blood cells of athletes is glutathione - S - transferase, compensatory increase in activity that reaches 630% relative to the level of the control group