Open AccessSTUDY OF PHARMACO-TOXICOLOGICAL PROPERTIES OF A QUATERNARY AMMONIUM COMPOUND THAT IS PART OF A DISINFECTANT
Author(s) -
F.M. Nekhaychik
Publication year - 2021
Publication title -
učenye zapiski kazanskoj gosudarstvennoj akademii veterinarnoj mediciny im. n.è. baumana
Language(s) - English
Resource type - Journals
ISSN - 2413-4201
DOI - 10.31588/2413-4201-1883-247-3-187-191
Subject(s) - disinfectant , ammonium , acute toxicity , median lethal dose , chemistry , toxicity , toxicology , pharmacology , nuclear chemistry , medicine , organic chemistry , biology
The study of the toxicological properties of a new disinfecting quaternary ammonium compound was carried out on laboratory animals of the vivarium of the Kazan State Medical University. Toxicological properties were evaluated on white mice, white rats, guinea pigs and rabbits by forming experimental and control groups. The value of acute oral toxicity, the indicator of the average lethal dose was experimentally determined, allergic properties were determined and the local irritant effect was evaluated. During the tests, it was found that the new quaternary ammonium compound belongs to the third hazard class.