Open AccessCOMBINED EFFECTS OF IONIZING RADIATION AND AGENTS OF BIOLOGICAL NA-TURE ON THE BODY OF ANIMALS
Author(s) -
Airat M. Idrisov,
Timur Gaynutdinov,
R.R. Timerbaeva,
Gulnaz Sh. Zakirova,
Konstantin N. Vagin,
Ya.M. Kurbangaleev
Publication year - 2021
Publication title -
učenye zapiski kazanskoj gosudarstvennoj akademii veterinarnoj mediciny im. n.è. baumana
Language(s) - English
Resource type - Journals
ISSN - 2413-4201
DOI - 10.31588/2413-4201-1883-246-2-98-103
Subject(s) - ionizing radiation , lesion , biology , lethal dose , radiation exposure , irradiation , physiology , toxicology , medicine , nuclear medicine , pathology , physics , nuclear physics
As a result of the work carried out, proceeding from the conceptual position of radiation parasitology about a certain commonality of the mechanisms of the pathogenic effect of ionizing radiation and parasitic agents on living organisms, we determined the conditions for modeling para-sitic invasion, as well as combined radiation-helminthic damage to the body using optimal doses of agents of invasive etiology. Irradiation of rabbits at a half-lethal dose of 7.0 Gy, produced before infection with passaluros at a dose of LD50 (1500 eggs of P. ambiguus), aggravates the course of the invasive process and promotes its generalization, accelerating the death of animals. The combined radiation-helminthic lesion proceeds quickly with the absolute death of all affected animals.