Open AccessDEVELOPMENT AND USE OF IRON PREPARATIONS AND PRINCIPLES THERAPY FOR IRON DEFICIENCY ANEMIA
Author(s) -
Н.А. Балакирев,
V.I. Maximov,
Alexander A. Deltsov
Publication year - 2021
Publication title -
učenye zapiski kazanskoj gosudarstvennoj akademii veterinarnoj mediciny im. n.è. baumana
Language(s) - English
Resource type - Journals
ISSN - 2413-4201
DOI - 10.31588/2413-4201-1883-246-2-19-25
Subject(s) - ferrous , ferric , iron deficiency anemia , anemia , hydroxide , iron supplement , iron deficiency , iron therapy , chemistry , physiology , medicine , organic chemistry
The key factor of non-infectious diseases of iron deficiency anemia, which slows down the growth and development of fur-bearing animals of various breeds, is a violation of iron metabolism in the body, which leads to a deterioration in the condition and quality of furs. This is due to the fact that iron is an essential element by which most of the processes and functions in the body are car-ried out. It has been shown that the use of preparations of ferrous and ferric iron leads to damage not only to the structural elements of the gastrointestinal tract, but also to other systems and organs, which is due to the fact that in the absence of oxygen in the tissues, the reduction of iron from the ferric form to the ferrous form with further transfer electrons from ferrous iron to hydrogen perox-ide causes the formation of a hydroxyl radical, which launches a program for self-destruction. It is proposed to solve the problem of the use of iron preparations for oral use in fur farming, as in-dustries where they are not used enough, to conduct research on the development and study of the effect of physiologically and pharmacologically active compounds based on a polymer (iron-hydroxide polymantose) on fur animals for the treatment and prevention of microelemetosis. It is being solved by the collective of the Department of Physiology, Pharmacology and Toxicology of the Moscow State Academy of Medical Sciences and Biology. Scriabin together with the research and production company LLC Firm "A-BIO" on the basis of an analysis of literary and patent sources, production technologies, pharmacological characteristics of ongoing research to develop and study the effect of physiologically and pharmacologically active compounds based on polymer (iron-hydroxide polymantose) on fur animals in the treatment and prevention of iron deficiency anemia.