Open AccessHEMODYNAMICS IN THE SKELETAL MUSCLES AND TEMPERATURE RESPONSE AF-TER SPINAL CORD INJURY
Author(s) -
N.V. Kubrak,
Н. А. Кононович
Publication year - 2021
Publication title -
učenye zapiski kazanskoj gosudarstvennoj akademii veterinarnoj mediciny im. n.è. baumana
Language(s) - English
Resource type - Journals
ISSN - 2413-4201
DOI - 10.31588/2413-4201-1883-246-2-112-117
Subject(s) - medicine , spinal cord injury , thermoregulation , heart rate , spinal cord , hemodynamics , hyperthermia , anesthesia , cord , cardiology , anatomy , blood pressure , surgery , psychiatry
The study purpose consisted in studying the dynamics of blood circulation in the muscles of distal segments of the pelvic limbs, as well as studying the temperature response after contusion in-jury of the spinal cord in small laboratory animals. Wistar female rats (n = 24) at the age of 8-10 months underwent modeling the spinal cord contusion injury of medium severity at the level of ТhIX. The dynamics of circulation in the mus-cles of the right and left leg, as well as local temperature response was studied on the body symmet-rical parts. Both the changes in the body overall temperature and the dynamics of heart rate were evaluated. The experiment duration was 90 days. The following was revealed: the signs of heart rate change – towards its decrease; the disor-der of thermoregulation processes was recorded throughout the experiment in the form of pro-nounced hyperthermia; the blood circulation in the leg muscles after one month of the experiment proceeded according to the hypokinetic type, which was subsequently changed to the hypertonicity of both large and small arteries. The disorders of venous outflow were not observed in this experi-ment. Locally, the changes of the temperature response and the functional vascular properties were more pronounced in the left limb.