Open AccessRESULTS OF STUDYING THE EMBRYOTOXIC ACTIVITY OF THE NEW COMPOUND "DS/16" IN WHITE RATS
Author(s) -
R.R. Gizzatullin,
R.R. Gizzatullina,
R.F. Shangaraev,
M.H. Lutfullin
Publication year - 2021
Publication title -
učenye zapiski kazanskoj gosudarstvennoj akademii veterinarnoj mediciny im. n.è. baumana
Language(s) - English
Resource type - Journals
ISSN - 2413-4201
DOI - 10.31588/2413-4201-1883-245-1-29-32
Subject(s) - pregnancy , fetus , white (mutation) , teratology , medicine , drug , toxicology , physiology , pharmacology , endocrinology , biology , genetics , gene
The embryotoxic activity of the compound "DS/16" was studied in white rats. It was found that when intragastric administration of the drug "DS/16" in animals at a dose of 60 mg / kg (1/20 part of a single dose of LD50), from 5-10 days of pregnancy, does not significantly affect the fetal embryonic development in the antenatal and postnatal period.