Multiple Endocrine Neoplasia Syndrome: Asymptomatic Primary Hyperparathyroidism: A perspective Study | Zendy

Wael El-Adl | Zendy; Serge Kreiter | Zendy; H. Suttmann | Zendy; Rania Farouk El Sayed | Zendy; A M Attia | Zendy

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Multiple Endocrine Neoplasia Syndrome: Asymptomatic Primary Hyperparathyroidism: A perspective Study

Author(s) -

Wael El-Adl,

Serge Kreiter,

H. Suttmann,

Rania Farouk El Sayed,

A M Attia

Publication year - 2017

Publication title -

endocrinology and disorders

Language(s) - English

Resource type - Journals

ISSN - 2640-1045

DOI - 10.31579/2640-1045/006

Subject(s) - primary hyperparathyroidism , medicine , asymptomatic , hyperparathyroidism , etiology , endocrine disease , disease , population , parathyroid hormone , endocrine system , intensive care medicine , pediatrics , bioinformatics , hormone , calcium , biology , environmental health

Hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.

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