Open AccessClinical, metabolic and hormonal features of the formation of impaired hypoglycemia awareness
Author(s) -
И А Рева,
AUTHOR_ID,
Ирина Аркадьевна Бондарь,
AUTHOR_ID
Publication year - 2021
Publication title -
journal of siberian medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2542-1174
DOI - 10.31549/2542-1174-2021-4-97-107
Subject(s) - hypoglycemia , diabetes mellitus , medicine , hormone , pathogenesis , disease , pregnancy , intensive care medicine , pediatrics , endocrinology , biology , genetics
The review presents the prevalence, pathogenetic aspects of the development of impaired hypoglycemia awareness in diabetes mellitus and its effect on the course of the disease. A key aspect in the pathogenesis of atypical hypoglycemias is the brain adaptation to a low glucose concentration in blood, which entails a disorder of hormonal response to hypoglycemia. This process is an autonomous dysfunction associated with hypoglycemia. It is noted the role of atypical hypoglycemia in the development of cardiovascular complications, cognitive impairments and pregnancy failure in patients with diabetes mellitus.