Open AccessThe responses of cholinergic system in the brain tissue of Van Fish (Alburnus tarichi) exposed to antifungal tebuconazole compound toxicity
Author(s) -
Aslı; VAN YUZUNCU YIL UNIVERSITY ÇİLİNGİR YELTEKİN
Publication year - 2022
Publication title -
aquatic research
Language(s) - English
Resource type - Journals
ISSN - 2618-6365
DOI - 10.3153/ar22010
Subject(s) - tebuconazole , toxicity , aché , acetylcholinesterase , fungicide , context (archaeology) , malondialdehyde , biology , toxicology , pharmacology , antioxidant , chemistry , botany , biochemistry , enzyme , paleontology , organic chemistry
Today, fungicide toxicity is quite common in aquatic ecosystems, and this situa-tion adversely affects ma-rine organisms. For this rea-son, it is essential to deter-mine the effects of fungi-cides on aquatic organisms and to try to prevent organ-isms from being exposed to these toxic chemicals. In this study, changes in cho-linergic system enzymes and (malondialdehyde) MDA levels as a result of exposure to acute fungicide toxicity in Van fish (Albur-nus tarichi, Güldenstädt 1814) were investigated. Brain tissue was taken from Van fish exposed to 2.5 M Tebuconazole used in agri-culture by sampling at 24, 48, 72, and 96 hours. Brain tissue acetylcholinesterase (AChE), butyrylcholinester-ase (BChE) activities, and MDA levels were measured in this context. In the study, AChE (0.965 ±0.03, 0.575±0.01) and BChE (0.421 ±0.02, 0,291 ±0.01) activities decreased in Van fish brain tissue due to ex-posure to Tebuconazole, but MDA (0.099 ±0.01, 0.192 ±0.01) level increased (p < 0.05).