
Progress on the study of fibroblast growth factors as novel therapeutics in post-stroke cognitive impairment
Author(s) -
Mengqi Li,
Hong Fan
Publication year - 2021
Publication title -
aging pathobiology and therapeutics
Language(s) - English
Resource type - Journals
ISSN - 2690-1803
DOI - 10.31491/apt.2021.09.065
Subject(s) - stroke (engine) , regulator , mechanism (biology) , fibroblast growth factor , medicine , hormone , cognition , homeostasis , fibroblast , neuroscience , psychology , biology , mechanical engineering , biochemistry , philosophy , receptor , epistemology , gene , engineering , in vitro
Post-stroke cognitive impairment (PSCI) is one of the most common complications after stroke, which severely affects the daily life abilities and social function of patients. Fibroblast growth factor (FGF), as a regulator of homeostasis, participates in the regulation of cell metabolism and hormone secretion, and can increase cerebral blood flow and promote nerve repair which improves PSCI. Here, we will conduct a review on the typing, characteristics, and mechanism of action of FGF to further understand its function and mechanism in PSCI