Open AccessAnti-inflammatory activity of a dental gel based on Origanum vulgare raw material
Author(s) -
С. Б. Ахметова,
AUTHOR_ID,
Karakoz Zhailovna Badekova,
Г. А. Атажанова,
Yana К. Levaya,
Marlen Kemelbekovich Smagulov,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2021
Publication title -
ķaraġandy universitetìnìṇ habaršysy. biologiâ, medicina, geografiâ seriâsy/k̦araġandy universitetìnìn̦ habaršysy. biologiâ, medicina, geografiâ seriâsy
Language(s) - English
Resource type - Journals
eISSN - 2663-5003
pISSN - 2518-7201
DOI - 10.31489/2021bmg4/91-96
Subject(s) - origanum , traditional medicine , antimicrobial , diclofenac sodium , anti inflammatory , essential oil , population , raw material , medicine , food science , chemistry , pharmacology , environmental health , organic chemistry
Inflammatory and destructive diseases of parodontosis are one of the most complex and common forms of the teeth diseases of human population. Search of the herbal preparation with anti-inflammatory activity is a prospect way for development of new drugs on the base of local raw material. A prerequisite for this study has been the presence of a high antimicrobial and anti-caries activity of the essential oil of medicinal plant Origanum vulgare. The article presents for the first time the results on the anti-inflammatory activity of dental anti-caries gel with essential oil and ethanol extract of oregano. A sample of dental gel at a dose of 25 mg / kg has anti-inflammatory activity, which was expressed in a significant decrease by 41.4 % in the amount of inflammatory lymph in the abdominal teeth in rats compared to controls. The anti-inflammatory activity of this sample is comparable to the reference drug diclofenac sodium.