Open AccessDetermination of antimicrobial activity of extracts from Melissa officinalis L.
Author(s) -
Nargiz Seidalina,
Saule Ahmetova,
Marlen Kemelbekovich Smagulov,
Г. А. Атажанова
Publication year - 2020
Publication title -
ķaraġandy universitetìnìṇ habaršysy. biologiâ, medicina, geografiâ seriâsy/k̦araġandy universitetìnìn̦ habaršysy. biologiâ, medicina, geografiâ seriâsy
Language(s) - English
Resource type - Journals
eISSN - 2663-5003
pISSN - 2518-7201
DOI - 10.31489/2020bmg4/79-84
Subject(s) - antimicrobial , melissa officinalis , bacillus subtilis , candida albicans , microbiology and biotechnology , biology , traditional medicine , minimum inhibitory concentration , escherichia coli , bacteria , chemistry , botany , medicine , biochemistry , genetics , gene
The constant growth of antibiotic resistance of bacteria creates the need for the development of antimicrobial drugs from extracts of medicinal plants. For the first time, the article presents the results of antimicrobial activity of extracts of Melissa officinallis L. (drug melissa) obtained by various methods, including ultrasonic extraction. The antimicrobial activity of the samples was studied in relation to strains of gram-positive bacteria Staphylocococus aureus, Bacillus subtilis, gram-negative strains Escherichia coli and yeast fungus Candida albicans. It was found that samples of aqueous extracts of drug melissa obtained by infusion and extraction by ultrasound have a pronounced antimicrobial effect on Staphylococus aureus, ultrasonic extracts of 30 % — and 90 % — alcohol extracts and water extract are active on Staphylocococus aureus and Bacillus subtilis and all samples showed weak activity The obtained data can be used for development of new phytopreparations with expressed antimicrobial activity.