Open AccessHyperuricemia and chronic kidney disease
Author(s) -
О. В. Компаниец
Publication year - 2021
Publication title -
ukraïnsʹkij žurnal nefrologìï ta dìalìzu
Language(s) - English
Resource type - Journals
eISSN - 2616-7352
pISSN - 2304-0238
DOI - 10.31450/ukrjnd.2(70).2021.09
Subject(s) - hyperuricemia , kidney disease , uric acid , nephron , pathogenesis , medicine , kidney , disease , gout , physiology , endocrinology , bioinformatics , biology
The article is devoted to a review of the literature on the impact of hyperuricemia on the development and progression of chronic kidney disease (CKD). The tendency of changes of views on the role of uric acid in the pathogenesis of CKD is demonstrated. An analysis of experimental, epidemiological and clinical studies on the effects of uric acid on the physiology of the nephron and endothelial tissues, the relationship of hyperuricemia with metabolic and cardiorenal syndromes.