ЗМІНА СТАНУ КОМПЛЕКСУ ЛЕГЕНЕВОГО СУРФАКТАНТУ ПРИ ВТРУЧАННЯХ З ПРИВОДУ ГОСТРОГО АОРТАЛЬНОГО СИНДРОМУ В УМОВАХ ШТУЧНОГО КРОВООБІГУ

Objective. To study changes in the state of pulmonary surfactant complex during interventions in acute aortic syndrome. Materials and methods. Biochemical analysis and cytological study were conducted on 142 samples obtained during the bronchoalveolar lavage performed intraoperatively or in the early postoperative period. Results. It was determined that in the postoperative period the bronchoalveolar fluid of patients with disorders of gas exchange contained significantly more general protein, albumin and fibrinogen, indicating an increase in the alveolar membrane transport. The higher content of plasma proteins in the alveolar fluid of patients with ARDS was due to low phospholipid content, reflecting damage to the lung surfactant system. Conclusion. The obtained data indicates the damage of pulmonary surfactant complex followed by an increase in the alveolar membrane transport leading to development of acute respiratory distress syndrome after surgery on the aorta.