Open AccessФУНКЦІОНАЛЬНИЙ СТАН ГУМОРАЛЬНОЇ ЛАНКИ ІМУНІТЕТУ ПРИ ТРАВМАТИЧНІЙ ХВОРОБІ У ПАЦІЄНТІВ З ПІДВИЩЕНИМ ІНДЕКСОМ МАСИ ТІЛА
Author(s) -
В В Кучерявченко,
Ю. В. Волкова,
К Ю Шарлай
Publication year - 2019
Publication title -
world science/world science
Language(s) - English
Resource type - Journals
eISSN - 2414-6404
pISSN - 2413-1032
DOI - 10.31435/rsglobal_ws/30042019/6473
Subject(s) - polytrauma , humoral immunity , medicine , disease , multivariate analysis , body mass index , surgery , immune system , immunology
The aim of our work was to analyze the functional state of the humoral immunity in traumatic disease in patients with an increased body mass index (IBMI). Using the systemic multivariate analysis, the integral indices of the B-system of immunogenesis were determined on the basis of a dynamic study of 1344 complex immunograms in 224 patients with IBMI with polytrauma with different starting figures for BMI in the period 1 day to 1 year from the moment of injury. Patients were divided into 3 groups depending on the starting BMI figures. It was revealed that changes in humoral processes in traumatic disease in patients with IBMI persist for a long time; the degree of damage to the B-system and the orientation of the reactions in the examined patients are of a similar nature; the manifestations and adequacy of the compensation processes and the severity of the acquired pathology of this subsystem depend on the patient's BMI, since the initial integral indicators in the comparison groups did not differ much.