Open AccessFEATURES OF THE COMORBID FLOW OF UNSTABLE STENOCARDIA AND THE ANXIETY-DEPRESSIVE SYNDROME DEPENDING ON THE BLOOD CYTOKINE LEVEL
Author(s) -
Насырова Зарина Акбаровна,
Ташкенбаева Элеонора Негматовна
Publication year - 2019
Publication title -
science review
Language(s) - English
Resource type - Journals
eISSN - 2544-9443
pISSN - 2544-9346
DOI - 10.31435/rsglobal_sr/30062019/6542
Subject(s) - medicine , unstable angina , anxiety , psychopathology , depression (economics) , acute coronary syndrome , angina , cardiology , clinical psychology , psychiatry , myocardial infarction , economics , macroeconomics
195 patients (102 men and 93 women) aged from 35 to 75 years (mean age 62.57 ± 0.75 years) suffering from unstable forms of IHD were examined on the basis of the SB RSCEMA in the emergency and cardiac resuscitation departments. All patients were tested using the Hospital Anxiety and Depression Scale. Based on the psychopathological examination data, all patients were divided into 2 groups. The first group included 109 patients with unstable angina with clinically significant affective disorders, which amounted to 55.89%. The second − the comparison group - 86 (44.1%) patients with unstable angina without affective disorders. Studies have shown that when comparing inflammatory markers − cytokines in patients with unstable angina, the pro-inflammatory cytokines IL-1 and TNFα are increased in individuals with comorbid pathology, depending on the presence or absence of affective disorders of the anxiety-depressive spectrum.