Open AccessAnxiety-depressive syndrome in patients with damage to the central nervous system by herpes viruses
Author(s) -
O. G. Andrieieva,
V. I. Yanchenko,
V. S. Vasylyk,
Polina A. Dyachenko,
L. V. Muravskya
Publication year - 2021
Publication title -
vìsnik vìnnicʹkogo nacìonalʹnogo medičnogo unìversitetu
Language(s) - English
Resource type - Journals
eISSN - 2522-9354
pISSN - 1817-7883
DOI - 10.31393/reports-vnmedical-2021-25(1)-10
Subject(s) - anxiety , depression (economics) , medicine , encephalitis , etiology , hospital anxiety and depression scale , meningoencephalitis , immunology , varicella zoster virus , herpes simplex virus , virus , psychiatry , economics , macroeconomics
Annotation. Purpose of work – a study of the prevalence and severity of anxiety-depressive syndrome based on the Hospital Anxiety and Depression Scale (HADS) in patients with damage to the nervous system of hepatic virus etiology. In this study, 2 groups of 30 people took part. The first group (main) is 30 people from a verified diagnosis of herpesviral damage to the nervous system aged 14 to 74 years. Viruses were in the stage of activation and persistence. The second group (control), almost healthy people – 30 people. There were 20 women and 10 men in each group. Diagnoses: Encephalitis, meningoencephalitis, arachnoencephalitis, arachnoiditis, disseminated encephalomyelitis, polyneuropathy, arachnoencephalopolyneuropathy, multiple sclerosis. Etiological factors were: HSV, EBV, VZV, HHV-7 + EBV, EBV + VZV, EBV + HSV, EBV + HHV-6, HSV + VZV, HSV + CMV + EBV + VZV, HSV + VZV + CMV + EBV + Tox.g. In all persons of the first group, a moderate course was observed. All subjects were tested on a hospital anxiety and depression scale (HADS). It was established that patients suffering from lesions of the nervous system of herpes virus etiology have signs of depression and anxiety. The duration in days of subclinically expressed depression in 9 people of the first group was 2.54±0.98, at p=0.04, and in the second group, depression not observed. Anxiety was subliminally expressed in the first group in 7 people, the duration in days was 4.20±1.20, and in the second group in 2 people, which was 1.0±0.69, with p=0.02. Thus, in patients with herpes virus lesions of the nervous system, anxiety-depressive syndrome is more pronounced than in practically healthy persons, perhaps this is due to damage to the limbic-diencephalic system of the brain.