Open AccessGenetic markers of One-Carbon Metabolism Disorders in Schizophrenial
Author(s) -
Г. Э. Мазо,
А. С. Пятойкина,
А С Благонравова,
Г. Э. Мазо
Publication year - 2019
Publication title -
obozrenie psihiatrii i medicinskoj psihologii im. v.m. behtereva/obozrenie psihiatrii i medicinskoj psihologii imeni v.m. behtereva
Language(s) - English
Resource type - Journals
eISSN - 2713-055X
pISSN - 2313-7053
DOI - 10.31363/2313-7053-2019-4-1-67-69
Subject(s) - single nucleotide polymorphism , snp , schizophrenia (object oriented programming) , genetics , biology , metabolism , genetic association , bioinformatics , medicine , genotype , psychiatry , biochemistry , gene
The paper presents the results of the literature review and the authors’ own studies of the association of several several single-nucleotide genetic polymorphisms (SNP), which affect one-carbon metabolism, with a risk of schizophrenia and the severity of some clusters of its symptoms. Directions for further study of the role of a number of SNP of enzymes in the folate metabolism cycle and related biochemical processes in schizophrenia (in particular, their influence on the effect of personalized correction of one-carbon metabolism disorders) are determined.