Spectroscopic Study for Determination of Amoxicillin Using Cobalt(II) as Complexing Metal
Author(s) -
May Mohammed Jawad Al-Mudhafar
Publication year - 2017
Publication title -
iraqi journal of pharmaceutical sciences ( p-issn 1683 - 3597 e-issn 2521 - 3512)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 1
eISSN - 2521-3512
pISSN - 1683-3597
DOI - 10.31351/vol18iss1pp65-71
Subject(s) - cobalt , amoxicillin , chemistry , metal , molar ratio , nuclear chemistry , solvent , chelation , inorganic chemistry , organic chemistry , catalysis , antibiotics , biochemistry
This study includes analytical methods for the determination of the drug amoxicillin trihydrate (Amox.) in some pharmaceutical preparations using Cobalt ion (Co(II)) as complexing metal. The best conditions for complexation were: the reaction time was 20 minutes, pH=1.5 and the best temperature of reaction was 70 ËšC. Benzyl alcohol was the best solvent for extraction the complex.
Keywords: Amoxicillin, Cobalt(II), Complex, Molar ratio.
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