Open AccessSynthesis and Characterization of 2(2-Tetrahydropyranylthio) methyl cyclopropylamine
Author(s) -
Zuhair Muhi-eldeen,
Samira F. Hassan
Publication year - 2017
Publication title -
iraqi journal of pharmaceutical sciences ( p-issn 1683 - 3597 e-issn 2521 - 3512)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 1
eISSN - 2521-3512
pISSN - 1683-3597
DOI - 10.31351/vol15iss1pp23-26
Subject(s) - radical , chemistry , thio , elemental analysis , proton nmr , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
2(2-Tetrahydropyranylthio) methyl cyclopropyl amines were synthesized from allylmercaptan through several steps. The structures of the intermediates and the final products where confirmed through IR, NMR and elemental analysis, these compounds may be of value in the treatment of diseases where free radicals are implicated in their pathogensis, since the thio and the amino groups of the synthesized compounds may act as free radical scavengers.
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