Open AccessA Study of the Furocoumarin Derivative of Ruta Chalepensis L. (Rutaceae)
Author(s) -
Ekbal Al-Khateeb,
Ali A. AL-Shamma,
Bajes A. Nehar
Publication year - 2017
Publication title -
al-maǧallaẗ al-’irāqiyyaẗ li-l-’ulūm al-ṣaydalāniyyaẗ/iraqi journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 1
eISSN - 2521-3512
pISSN - 1683-3597
DOI - 10.31351/vol15iss1pp10-15
Subject(s) - furocoumarin , psoralen , bergapten , chromatography , chemistry , rutaceae , furocoumarins , methoxsalen , petroleum ether , derivative (finance) , furanocoumarin , chromone , ether , extraction (chemistry) , organic chemistry , biology , botany , dna , psoriasis , biochemistry , photochemistry , economics , financial economics , immunology
The content of Furocoumarin derivatives (Psoralens) of Ruta Chalepensis L. (Whole plant) was studied by simple extraction with petroleum ether (b.p. 60-80Co). The results indicated that the plant contains a total of about (0.015%).
Investigation of these compounds by thin layer chromatography (TLC) revealed the presence of at least four compounds of which methoxsalen (8-methoxypsoralen) was isolated. It was identified and authenticated with a standard by spectral method, IR, NMR, Mass spectra and HPLC.This plant could be considered as a good source for supplying this compound, which is widely used in dermatological preparations.