Liver Function Test on HBsAg Positive Blood Donors | Zendy

Amrit MS Maharjan | Zendy; Bharat Jha | Zendy; Anjana Singh | Zendy

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Liver Function Test on HBsAg Positive Blood Donors

Author(s) -

Amrit MS Maharjan,

Bharat Jha,

Anjana Singh

Publication year - 2018

Publication title -

tribhuvan university journal of microbiology

Language(s) - English

Resource type - Journals

eISSN - 2661-6076

pISSN - 2382-5499

DOI - 10.3126/tujm.v4i0.21668

Subject(s) - hbsag , alkaline phosphatase , albumin , medicine , liver function , liver function tests , gastroenterology , hepatitis b , alanine aminotransferase , serum albumin , alanine transaminase , hepatitis b virus , immunology , chemistry , enzyme , virus , biochemistry

Objectives: The study was done to assess liver function test among hepatitis B surface antigen (HBsAg) positive blood donors.Methods: Liver function test (LFT) were studied in 71 HBsAg positive serum samples from healthy blood donors.Results: In the study, 14(19.7Ü) serum samples showed elevated alanine aminotransferase (ALT) level above the normal range (5_35 IU/I) with mean 66.3±27.6; 16(22.5%) showed aspartate aminotransferase (AST) level above the normal range (5-40 IU/I) with mean 87.5±35.7; 4(5.6%) serum samples showed alkaline phosphatase (ALP) level above the normal range (306 IU/I) with mean 376.5±31.5; 49(69%) samples were found to be below the normal albumin level (38-51gm/I) with mean 23.9±5.76.Conclusion: Deviations in the serum enzymes (ALT, AST and ALP) as well as total protein and albumin level showed the silent infection of hepatitis B virus in healthy blood donors.

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