Open AccessAssociation of Socio-Demographic Profile with Prevalence of Multi Drug Resistant Tuberculosis among Retreated Pulmonary Tuberculosis Patients in North India
Author(s) -
Anjali Chaudhary,
Tariq Mahmood,
Amitabh Das Shukla,
A Shreenivasa,
Verma Arvind,
Kaleem Ahmad,
Ashish Verma
Publication year - 2018
Publication title -
saarc journal of tuberculosis, lung diseases and hiv/aids
Language(s) - English
Resource type - Journals
ISSN - 1818-9741
DOI - 10.3126/saarctb.v16i1.23238
Subject(s) - medicine , tuberculosis , sputum , pulmonary tuberculosis , rifampicin , cross sectional study , observational study , multi drug resistant tuberculosis , mycobacterium tuberculosis , pathology
Methods: An observational cross sectional study, which includes 116 patients of sputum smear positive pulmonary TB of age 18 or above. Further, detailed history taking regarding different demographic profile was done. Also, they were subjected to CB-NAAT and rifampicin resistant cases were considered as MDR-TB.
Results: Proportion of MDR-TB was 31.89% among retreatment TB cases. 56.75 % (n=21) of MDR-TB cases were between the age group of 21-40 years. Proportion of MDR-TB was higher among males (75.67%), married (59.45%) and rural dwellers 59.45%. Proportion was 61.76% among patients with BMI <16; 31.57% with BMI 16-16.99, 28.57% with BMI 17-18.49 and 5.7% with BMI 18.50-24.99. MDRTB proportion was less 29.72% (n=11) in patients with history of TB contact in family. Pulmonary TB including MDR-TB was more common among illiterates (37.83% among MDR).
Conclusion: Proportion of MDR-TB was high among retreatment cases in north India. Among them low BMI and education status are modifiable factor and this study signifies that MDR-TB burden can be reduced by improving health and education status of patient.