Open AccessPerimenopausal invasive complete hydatidiform mole: a rare encounter
Author(s) -
Aasiya Rajbhandari,
Karishma Malla Vaidya,
Bibhuti Dahal
Publication year - 2022
Publication title -
journal of pathology of nepal
Language(s) - English
Resource type - Journals
eISSN - 2091-0797
pISSN - 2091-0908
DOI - 10.3126/jpn.v12i1.33932
Subject(s) - medicine , hysterectomy , mole , gynecology , chorionic villi , obstetrics , chemotherapy , gestational trophoblastic disease , pregnancy , gestation , surgery , fetus , prenatal diagnosis , biology , genetics
Invasive mole, classified under the gestational trophoblastic diseases, comprises of hydropic chorionic villi invading the underlying myometrium, blood vessels or extra-uterine sites. They are usually diagnosed clinically and are treated with chemotherapy. Thus, surgery is rarely performed owing to good response to chemotherapy and preservation of fertility, since most women are in reproductive age. Thus, these specimens are rarely encountered by the pathologists. Here, we report a case of invasive mole in a 48 year old female with persistent elevation of serum beta HCG levels and completed family status who underwent hysterectomy and was diagnosed as a case of invasive mole on histopathologic examination.